Efficacy and Safety of Prescription Libido Aids
With DARE to PLAY Sildenafil Cream, you can feel confident in what you’re using – every single time.
THE BIG “O” (OVERVIEW)
With DARE to PLAY Sildenafil Cream, you can feel confident in what you’re using – every single time. This is the first clinical study of its kind to demonstrate that this specific topical formulation of sildenafil, DARE to PLAY Sildenafil Cream, can support genital blood flow and arousal in women. Offering a non-hormonal option with a faster onset (10–15 minutes) and fewer side effects than oral medications, it represents a significant breakthrough for female sexual health. Daré’s proprietary formulation of Sildenafil Cream was evaluated in the RESPOND Study, the first-ever randomized, double-blind, placebo-controlled clinical trial for a topical treatment targeting Female Sexual Arousal Disorder (FSAD) submitted to the FDA. This Phase 2b trial included 200 premenopausal women experiencing symptoms of FSAD, such as reduced genital sensation and frustration during intimacy.
What happens when females take Viagra?
Safety Profile: The side effect profile of DARE to PLAY Sildenafil Cream was similar to placebo (cream without sildenafil added), with no serious safety concerns reported. Study Results:Women using DARE to PLAY Sildenafil Cream experienced the following improvements, as measured by clinically validated and FDA-reviewed endpoints: Reduced feelings of sexual distress and interpersonal difficulties resulting from the sexual difficulties In the Phase 2b trial, after 12 weeks, women who used DARE to PLAY Sildenafil Cream reported statistically significant and clinically meaningful improvements in genital arousal sensation (warmth and tingling) compared to those who used placebo cream. On average, Arousal Sensation scores (measured by a patient-reported questionnaire) increased by over 2 points with DARE to PLAY Sildenafil Cream, compared to almost no change with placebo cream. Women who used DARE to PLAY Sildenafil Cream also showed improvement across other key areas of sexual function, including desire and orgasm. Results shown are from a subset of 65 women in a 12-week clinical trial: 33 women who received Sildenafil Cream and 32 who received Placebo Cream.
What causes low libido in women?
The results were published in the Green Journal (Obstetrics & Gynecology), the official journal of the American College of Obstetricians and Gynecologists (ACOG) and highlighted on ACOG’s podcast The Green Room. Clinical trial results were also featured in The Journal of Sexual Medicine, the official journal of the International Society for the Study of Women’s Sexual Health. DARE to PLAY is the only sildenafil cream for women supported by published, peer-reviewed clinical data. It was studied in clinical trials that used clinically validated and FDA-reviewed endpoints to measure results. The cream is designed with a proprietary drug delivery system that helps sildenafil get into the vaginal and vulvar tissue, where it can act locally to increase blood flow. This is the first clinical study of its kind to demonstrate that this specific topical formulation of sildenafil, DARE to PLAY Sildenafil Cream, can support genital blood flow and arousal in women. Offering a non-hormonal option with a faster onset (10–15 minutes) and fewer side effects than oral medications, it represents a significant breakthrough for female sexual health. Daré’s proprietary formulation of Sildenafil Cream was evaluated in the RESPOND Study, the first-ever randomized, double-blind, placebo-controlled clinical trial for a topical treatment targeting Female Sexual Arousal Disorder (FSAD) submitted to the FDA. This Phase 2b trial included 200 premenopausal women experiencing symptoms of FSAD, such as reduced genital sensation and frustration during intimacy. Safety Profile: The side effect profile of DARE to PLAY Sildenafil Cream was similar to placebo (cream without sildenafil added), with no serious safety concerns reported. Study Results:Women using DARE to PLAY Sildenafil Cream experienced the following improvements, as measured by clinically validated and FDA-reviewed endpoints: Reduced feelings of sexual distress and interpersonal difficulties resulting from the sexual difficulties In the Phase 2b trial, after 12 weeks, women who used DARE to PLAY Sildenafil Cream reported statistically significant and clinically meaningful improvements in genital arousal sensation (warmth and tingling) compared to those who used placebo cream. On average, Arousal Sensation scores (measured by a patient-reported questionnaire) increased by over 2 points with DARE to PLAY Sildenafil Cream, compared to almost no change with placebo cream. Women who used DARE to PLAY Sildenafil Cream also showed improvement across other key areas of sexual function, including desire and orgasm. Results shown are from a subset of 65 women in a 12-week clinical trial: 33 women who received Sildenafil Cream and 32 who received Placebo Cream. The results were published in the Green Journal (Obstetrics & Gynecology), the official journal of the American College of Obstetricians and Gynecologists (ACOG) and highlighted on ACOG’s podcast The Green Room. Clinical trial results were also featured in The Journal of Sexual Medicine, the official journal of the International Society for the Study of Women’s Sexual Health.
- Research is ongoing into new drug targets, like melanocortins and oxytocin.
- Lybrido and Lybridos were combination drugs (testosterone/sildenafil) investigated.
- The EROS-CTD device is an example of a non-hormonal, device-based treatment.
- Gene therapy and other novel approaches are in very early stages of research.
- Future treatments may offer more personalized approaches based on individual biology.
- Digital therapeutics and app-based cognitive behavioral therapy are emerging.
- The field is moving towards treating the combined psychological and biological causes.
DARE to PLAY is the only sildenafil cream for women supported by published, peer-reviewed clinical data. It was studied in clinical trials that used clinically validated and FDA-reviewed endpoints to measure results. The cream is designed with a proprietary drug delivery system that helps sildenafil get into the vaginal and vulvar tissue, where it can act locally to increase blood flow.
| Question | Answer | Additional Info |
|---|---|---|
| Is female viagra available over the counter in UK? | No, it requires a prescription | Currently, no OTC option in UK |
| How long does it take to work? | Usually within 30-60 minutes | Varies per individual |
| Are there natural alternatives? | Yes, herbal supplements and lifestyle changes | Consult a healthcare provider |
| Can I buy female viagra online safely? | Only from licensed and reputable sources | Beware of scams and counterfeit products |
Other sildenafil creams on the market haven’t been proven to work–they have not been studied, shown to absorb properly or published in peer-reviewed research, and are often compounded viagra tablet for sex without consistent quality standards.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Professional | 100mg | 20 Pills | 71.14€ 67.75€ | |
| Viagra Generic | 25mg | 20 Pills | 37.74€ 35.94€ | |
| Viagra Generic | 150mg | 180 + 10 Pills | 236.46€ 225.20€ | |
| Viagra Original | 100mg | 76 + 4 Pills | 306.59€ 291.99€ | |
| Viagra Original | 100mg | 8 Pills | 59.84€ 56.99€ | |
| Viagra Original | 100mg | 4 Pills | 40.94€ 38.99€ | |
| Viagra Generic | 150mg | 120 + 8 Pills | 177.58€ 169.12€ | |
| Viagra Professional | 100mg | 30 Pills | 88.92€ 84.69€ | |
| Viagra Generic | 100mg | 90 + 6 Pills | 129.02€ 122.88€ | |
| Viagra Generic | 50mg | 60 + 4 Pills | 83.93€ 79.93€ | |
| Viagra Professional | 100mg | 10 Pills | 44.09€ 41.99€ | |
| Viagra Original | 100mg | 14 + 2 Pills | 89.03€ 84.79€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ | |
| Viagra Generic | 200mg | 360 + 10 Pills | 481.98€ 459.03€ | |
| Viagra Original | 100mg | 34 + 2 Pills | 163.67€ 155.88€ | |
| Viagra Generic | 25mg | 120 + 6 Pills | 125.56€ 119.58€ |
DARE to PLAY stands apart because it’s rigorously developed, science-backed, and held to the highest standards of quality and clinical evidence. Sildenafil (the active ingredient in Viagra®) has a long-established safety profile in men. The topical formulation used in DARE to PLAY is designed to work locally (in the tissues that matter for sexual arousal) while minimizing how much of the drug enters the bloodstream. DARE to PLAY has been evaluated in clinical studies and was well tolerated, with no significant safety concerns reported.
The #1 Prescribed Treatment for frustrating Low Libido1
Other sildenafil creams on the market haven’t been proven to work–they have not been studied, shown to absorb properly or published in peer-reviewed research, and are often compounded viagra tablet for sex without consistent quality standards. DARE to PLAY stands apart because it’s rigorously developed, science-backed, and held to the highest standards of quality and clinical evidence. Sildenafil (the active ingredient in Viagra®) has a long-established safety profile in men. The topical formulation used in DARE to PLAY is designed to work locally (in the tissues that matter for sexual arousal) while minimizing how much of the drug enters the bloodstream. DARE to PLAY has been evaluated in clinical studies and was well tolerated, with no significant safety concerns reported.
Let's do it.
The safety findings from the Phase 2b clinical study have been published and are available on the DARE to PLAY website. If you experience difficulty with sexual arousal, including a lack of physical response or reduced genital sensitivity during sexual activity, you may benefit from DARE to PLAY. A conversation with a licensed healthcare provider can help determine whether it is appropriate for you. DARE to PLAY contains the same active ingredient as Viagra®, but it’s formulated specifically for women and applied directly where it’s needed. Unlike an oral pill, DARE to PLAY is a topical cream designed to work locally rather than systemically.
Though you cannot place an order quite yet...
Apply the cream with your finger 10 to 15 minutes before sexual activity up to once per day. Slowly squeeze out a length of cream about 2 ½ inches long for one 2-gram dose. Lying on your back, apply half the cream on and around the clitoris and the area around the vaginal opening, avoiding areas with hair. Apply the rest of the cream just inside the vagina, rubbing the cream with a curved finger on the front wall of the vagina. Once applied, do not wipe off any of the cream until after sexual activity. The safety findings from the Phase 2b clinical study have been published and are available on the DARE to PLAY website.
- The first FDA-approved female libido drug was flibanserin, marketed as Addyi in the US and sometimes available in the UK.
- Female Viagra aims to target conditions like low libido, which can be caused by hormonal or psychological issues.
- The effectiveness of female Viagra varies between individuals; some report notable improvements.
- Cost of female libido medications in the UK varies and may not be covered by NHS prescriptions.
- Researchers continue to explore new treatments for female sexual dysfunction with promising results.
- Natural alternatives include herbal supplements like ginseng or maca, but their efficacy is not well-proven.
- Discussing sexual health openly with a healthcare professional is recommended before starting treatment.
- Some women use off-label medications or supplements to boost libido, but safety isn't always assured.
- Female Viagra is not suitable for everyone; medical history and other medications should be considered.
If you experience difficulty with sexual arousal, including a lack of physical response or reduced genital sensitivity during sexual activity, you may benefit from DARE to PLAY. A conversation with a licensed healthcare provider can help determine whether it is appropriate for you. DARE to PLAY contains the same active ingredient as Viagra®, but it’s formulated specifically for women and applied directly where it’s needed. Unlike an oral pill, DARE to PLAY is a topical cream designed to work locally rather than systemically. Apply the cream with your finger 10 to 15 minutes before sexual activity up to once per day. Slowly squeeze out a length of cream about 2 ½ inches long for one 2-gram dose. Lying on your back, apply half the cream on and around the clitoris and the area around the vaginal opening, avoiding areas with hair. Apply the rest of the cream just inside the vagina, rubbing the cream with a curved finger on the front wall of the vagina. Once applied, do not wipe off any of the cream until after sexual activity. In the Phase 2b clinical study, women did not use lubricants because the study was specifically designed to evaluate the impact of DARE to PLAY on the genital arousal response. However, there are no concerns about the compatibility of lubricants with the DARE to PLAY formulation. DARE to PLAY has been studied in both pre-and postmenopausal women to evaluate safety, tolerability, and how the drug is absorbed in the body (pharmacokinetics). In these studies, the cream was well tolerated. The Phase 2b clinical study enrolled healthy pre-and perimenopausal women aged 18 to 45 who had a diagnosis of Female Sexual Arousal Disorder (FSAD). Similar to FDA-approved products for Hypoactive Sexual Desire Disorder (HSDD), FSAD trials conducted for FDA review typically focus on either pre-or postmenopausal populations. In the Phase 2b clinical study, approximately one-third of the participants were taking an SSRI. An informal analysis compared women on SSRIs with those who were not and found that both groups showed positive trends in improved arousal sensations. Many vaginal products contain ingredients that buy viagra connect online can weaken condoms, increasing the risk of breakage. DARE to PLAY was tested using ASTM D7661-10, a standardized method that ensures a product is safe to use with condoms.
MEET OUR LOW LIBIDO TREATMENT
In the Phase 2b clinical study, women did not use lubricants because the study was specifically designed to evaluate the impact of DARE to PLAY on the genital arousal response. However, there are no concerns about the compatibility of lubricants with the DARE to PLAY formulation. DARE to PLAY has been studied in both pre-and postmenopausal women to evaluate safety, tolerability, and how the drug is absorbed in the body (pharmacokinetics). In these studies, the cream was well tolerated. The Phase 2b clinical study enrolled healthy pre-and perimenopausal women aged 18 to 45 who had a diagnosis of Female Sexual Arousal Disorder (FSAD).
Side effects
Similar to FDA-approved products for Hypoactive Sexual Desire Disorder (HSDD), FSAD trials conducted for FDA review typically focus on either pre-or postmenopausal populations. In the Phase 2b clinical study, approximately one-third of the participants were taking an SSRI. An informal analysis compared women on SSRIs with those who were not and found that both groups showed positive trends in improved arousal sensations. Many vaginal products contain ingredients that buy viagra connect online can weaken condoms, increasing the risk of breakage. DARE to PLAY was tested using ASTM D7661-10, a standardized method that ensures a product is safe to use with condoms.
Key takeaways
Based on these tests, DARE to PLAY is compatible with all male condoms except those made of polyurethane. In the Phase 2b clinical study, women were allowed to use DARE to PLAY during oral sex, and it was well tolerated with no significant safety concerns. Prior to the Phase 2b clinical study, DARE to PLAY was also tested in a preclinical study to assess its effects on the oral mucosa. These tests showed that daily exposure for 28 days did not cause irritation inside the mouth. The DARE to PLAY formulation does contain a proprietary combination of salts that support the absorption of sildenafil into the tissue. Based on these tests, DARE to PLAY is compatible with all male condoms except those made of polyurethane.
The Big Pink Fight for the Little Pink Pill
As a result, you may notice a mildly salty taste. DARE to PLAY can be used in both situations! In the Phase 2b clinical study, about 20% of sexual events were solo, and women reported that these experiences were often more satisfying than partnered events. Partnered events sometimes occurred under less-than-ideal conditions, like limited time or distractions, which can affect pleasure. DARE to PLAY is designed to complement, not replace, other approaches.
Interactions with other medications
It is a pharmacologic option focused on improving genital blood flow and physical responsiveness. Women often benefit most from a multimodal approach. DARE to PLAY is designed to improve physical arousal by increasing genital blood flow. Many women find that enhancing physical responsiveness can also help restore desire and confidence. In the Phase 2b clinical study, women with low desire due to diminished physical arousal sensations experienced improved desire following use of DARE to PLAY.
Exploratory Phase 2b RESPOND Study, Completed in 2023
If low desire is influenced by emotional or relationship factors, combining DARE to PLAY with other approaches—like counseling or therapy—may provide the best results. Yes, please see these instructions for how to get a prescription. Anyone who is licensed to write prescriptions can prescribe it—including your primary care provider (PCP), family medicine doctor, OB/GYN, nurse practitioner, physician assistant, or another qualified specialist. The DARE Health Hub (powered by Medvantx) is a nationwide pharmacy and telehealth service. Whether you use the DARE Health Hub telehealth offering to get your prescription or get a prescription from your provider, this is where you will order/fill your prescription. In the Phase 2b clinical study, women were allowed to use DARE to PLAY during oral sex, and it was well tolerated with no significant safety concerns. Prior to the Phase 2b clinical study, DARE to PLAY was also tested in a preclinical study to assess its effects on the oral mucosa. These tests showed that daily exposure for 28 days did not cause irritation inside the mouth. The DARE to PLAY formulation does contain a proprietary combination of salts that support the absorption of sildenafil into the tissue.
- The topic is often sensationalized in media as a search for a "pink Viagra."
- This can create unrealistic expectations about a simple pill solving complex issues.
- Ethical debates concern medicalizing normal variations in female sexual desire.
- The high cost of new drugs creates issues of accessibility and healthcare inequality.
- Off-label use of testosterone is common but lacks long-term safety data for women.
- The primary focus should be on treating the underlying cause, not just the symptom.
- Patient education and managing expectations are a critical part of the process.
As a result, you may notice a mildly salty taste. DARE to PLAY can be used in both situations! In the Phase 2b clinical study, about 20% of sexual events were solo, and women reported that these experiences were often more satisfying than partnered events. Partnered events sometimes occurred under less-than-ideal conditions, like limited time or distractions, which can affect pleasure. DARE to PLAY is designed to complement, not replace, other approaches. It is a pharmacologic option focused on improving genital blood flow and physical responsiveness. Women often benefit most from a multimodal approach. DARE to PLAY is designed to improve physical arousal by increasing genital blood flow. Many women find that enhancing physical responsiveness can also help restore desire and confidence.
- A GP is the first point of contact for discussing sexual health concerns in the UK.
- They may conduct blood tests to check hormone levels (e.g., testosterone, estrogen).
- A full medical and psychological history is essential for an accurate diagnosis.
- GPs can refer patients to a specialist clinic, like a urogynaecology or sexual health service.
- Specialists may work in NHS hospitals or private practices.
- The British Society for Sexual Medicine provides guidelines for healthcare professionals.
- A diagnosis often involves ruling out other medical and relationship issues first.
In the Phase 2b clinical study, women with low desire due to diminished physical arousal sensations experienced improved desire following use of DARE to PLAY.
We got busy with a full clinical study.
This service offers contact-free ordering and discreet delivery directly to your doorstep. Here’s what you can expect depending on your preferred method of obtaining a prescription: viagra alternative uk Register for an account at the DARE Health Hub. After registering, you will be asked, “Have you seen a provider already?” Select “No” to initiate a telehealth consultation. You’ll then be asked to: Provide your address informationSign the telehealth consent agreementFill out the telehealth questionnaireVerify your identification (by uploading a photo ID) Verify your identification (by uploading a photo ID) Within approximately 24 hours, your telehealth questionnaire responses will be reviewed by a licensed healthcare provider, and if medically appropriate, you will receive a prescription for DARE to PLAY. You can check the status of your prescription under “My Prescriptions” in the DARE Health Hub. If low desire is influenced by emotional or relationship factors, combining DARE to PLAY with other approaches—like counseling or therapy—may provide the best results. Yes, please see these instructions for how to get a prescription. Anyone who is licensed to write prescriptions can prescribe it—including your primary care provider (PCP), family medicine doctor, OB/GYN, nurse practitioner, physician assistant, or another qualified specialist. The DARE Health Hub (powered by Medvantx) is a nationwide pharmacy and telehealth service. Whether you use the DARE Health Hub telehealth offering to get your prescription or get a prescription from your provider, this is where you will order/fill your prescription. This service offers contact-free ordering and discreet delivery directly to your doorstep. Here’s what you can expect depending on your preferred method of obtaining a prescription: viagra alternative uk Register for an account at the DARE Health Hub. After registering, you will be asked, “Have you seen a provider already?” Select “No” to initiate a telehealth consultation. You’ll then be asked to: Provide your address informationSign the telehealth consent agreementFill out the telehealth questionnaireVerify your identification (by uploading a photo ID) Verify your identification (by uploading a photo ID) Within approximately 24 hours, your telehealth questionnaire responses will be reviewed by a licensed healthcare provider, and if medically appropriate, you will receive a prescription for DARE to PLAY. You can check the status of your prescription under “My Prescriptions” in the DARE Health Hub. You will be notified in the coming months, via email and text message, when ordering becomes available in your state. Ordering details will be added once available! Talk to your healthcare provider about DARE to PLAY.
Find out if treatment is right for you.
You will be notified in the coming months, via email and text message, when ordering becomes available in your state. Ordering details will be added once available! Talk to your healthcare provider about DARE to PLAY. Bring the prescribing guide with you to your appointment. If your provider feels DARE to PLAY is medically appropriate for you, they will submit your prescription directly to the DARE Health Hub. Bring the prescribing guide with you to your appointment. If your provider feels DARE to PLAY is medically appropriate for you, they will submit your prescription directly to the DARE Health Hub. You will then receive a phone call from the DARE Health Hub confirming receipt of your prescription and inviting you to register for an account. After registering, you’ll receive timely updates and a notification as soon as your prescription is ready to be ordered through the DARE Health Hub in the coming months. Compounded medications like DARE to PLAY are typically not covered by insurance.
How DARE to PLAY Sildenafil Cream Works
You will then receive a phone call from the DARE Health Hub confirming receipt of your prescription and inviting you to register for an account. After registering, you’ll receive timely updates and a notification as soon as your prescription is ready to be ordered through the DARE Health Hub in the coming months. Compounded medications like DARE to PLAY are typically not covered by insurance.
