FDA Approves First Pill to Boost Sex Drive in Women After Menopause

If you’re in a hurry, here’s a quick summary of our findings. Best over-the-counter pill: Promescent VitaFLUX Best (and fastest) prescription pill: Cake Meds Libido Lift Rx for Her Runner-up OTC pill: Hello Cake Drive For Her Best over-the-counter topical: Unbound Jolt Gel Promescent’s VitaFLUX is a non-prescription alternative that can improve libido, arousal, and natural lubrication in women. This vegan-friendly supplement relies on magnesium, zinc, and three amino acids — all of which research suggests can boost nitric oxide production and improve many symptoms of sexual dysfunction.

• Natural supplements versus synthetic options
• The role of aphrodisiacs in sex tablets
• How sex tablets influence blood flow and arousal
• Consulting a doctor before use of sex pills
• The importance of dosage in effectiveness and safety
• Common myths about women’s sex enhancement pills
• Dietary considerations when using sex tablets
• Potential interactions with other medications
• The psychological benefits of improved libido
• How long it takes for sex tablets to work
• Criteria for recognizing fake or counterfeit pills

Promescent offers our readers an exclusive $5 off at checkout when clicking any link on this page. Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. For this review of the best female cenforce 100 soft arousal products, we pored over dozens of scientific studies and articles on safe and effective ingredients, and our team thoroughly investigated the companies behind the products. Our testers also purchased these items so that we could compare them and provide detailed explanations (such as differences in pill size).

Brand Name	Active Ingredients	Recommended Dosage	Price Range ($)	Availability
LibidoMax	L-arginine, Maca	1 tablet daily	15-30	Online & Stores
AphroViva	Yohimbine, Ginseng	2 capsules before intimacy	25-40	Online only
DesirePlus	Horny Goat Weed	1 capsule per day	20-35	Pharmacies & Online
FemVibe	L-arginine, Tribulus	1-2 tablets per day	18-32	Online retailers
Eros Boost	Maca, Ginseng	1 tablet daily	22-38	Health stores

As more information on new products and ingredients becomes available, we’ll update this review accordingly. Additionally, like all health-related content on this website, this guide was thoroughly vetted for accuracy by one or more members of our Medical Review Board.

What is addyi?

It works by decreasing neurotransmitters that interfere with the sex drive and increasing neurotransmitters (such as dopamine) that improve desire. Vyleesi is a non-hormonal on-demand injection. Vyleesi must be injected a minimum of 45 minutes before being sexual and its effects last 16 hours. It rebalances brain chemistry, allowing the stimulation of excitement neurotransmitters while slowing down neurotransmitters that inhibit desire. While there are no FDA-approved options for increasing desire in post-menopausal women, topical testosterone used off-label can be helpful.

How is low sex drive diagnosed in women?

Testosterone in gel or pump form is adjusted to a female dose equaling one-tenth of the male dose and used topically. It is effective in about 60 percent of women. Problems with sexual arousal can also negatively affect sexual desire. Over-the-counter lubricants and vaginal moisturizers as well as prescription hormone treatments can improve arousal and support desire. Vaginal estrogen and DHEA are used to treat postmenopausal women who have changes in vaginal tissue due to a loss of estrogen.

DAMIANA EXTRACT

Vaginal estrogen comes in tablets, gel caps, rings and creams. DHEA is offered in a vaginal suppository. A pill, Osphena, is a non-hormonal treatment known as a SERM (selective estrogen increase libido in women receptor modulator). Available by prescription only, vaginal estrogen, vaginal DHEA and Osphena help restore vaginal tissue that has become thinner and dryer. They may also help improve sensation and natural lubrication as tissue is restored to health. There is a wide variety of female arousal pills, gels, creams, and other products on the market. With some containing less-than-safe ingredients, it’s important to know which libido-support products for women are safe and effective. We also evaluated these products based on how burdensome (or not) the cost may be and how convenient they are to acquire and use.

• How to read labels and ingredient lists accurately
• The importance of transparency from manufacturers
• Common misconceptions about female libido pills
• Natural ways to boost female arousal without pills
• The effect of menstrual cycles on pill effectiveness
• Non-invasive alternatives to enhance sexual pleasure
• Differences between herbal and synthetic pills
• The role of pelvic floor exercises in sexual satisfaction
• How to identify genuine product sources
• The importance of avoiding expired pills
• Ethical considerations around sexual health products

Unlike the sketchy “instant female arousal pill” products on the market, our top picks overwhelmingly rely on safe ingredients.

Product	Dosage	Quantity + Bonus	Price
Kamagra 100 mg	100 mg	20 Pills	86.09€ 81.99€	Buy
Viagra Soft Tabs	100mg	270 + 10 Pills	419.95€ 399.95€	Buy
Cialis Generic	5mg	30 + 4 Pills	53.56€ 51.01€	Buy
Cialis Super Active	20mg	180 + 20 Pills	521.59€ 496.75€	Buy
Cialis Generic	20mg	90 + 6 Pills	154.71€ 147.34€	Buy
Cialis Professional	20mg	180 + 4 Pills	423.11€ 402.96€	Buy
Priligy Generic Dapoxetine	60mg	90 + 10 Pills	265.64€ 252.99€	Buy
Cialis Generic	5mg	180 + 10 Pills	159.65€ 152.05€	Buy
Levitra Original	20mg	22 + 2 Pills	138.55€ 131.95€	Buy
Viagra Super Active	100mg	60 + 8 Pills	116.84€ 111.28€	Buy
Kamagra	100mg	20 Pills	86.09€ 81.99€	Buy
Kamagra 100 mg	100 mg	120 + 6 Pills	330.74€ 314.99€	Buy

Our choice for the best over-the-counter (OTC) pill, VitaFLUX, only uses five active ingredients: L-arginine, L-citrulline, L-carnitine tartrate, magnesium, and zinc. These amino acids and minerals should be safe for most people to take.

Country/Region	Regulatory Body	Regulation Level	Requirements	Notable Restrictions
USA	FDA	Strict	Must be approved, safe ingredients	Ban on unapproved claims
EU	EMA, national agencies	Moderately strict	Clinical trials, labeling	Ingredient restrictions
Australia	TGA	Strict	Safety testing, registration	Claims verification
China	CNCA	Varies	Sometimes less regulated	Quality standards adherence
Russia	Rospotrebnadzor	Moderate	Certification required	Ingredient testing mandated

However, there are some instances where an alternative might be better for you. For example, taking L-arginine could trigger a herpes flare-up (both HSV-1 and HSV-2), and L-carnitine may interact with certain thyroid medications.3 4 So, as always, we recommend consulting your doctor before starting a supplement to ensure it’s safe for you. Overall, though, the ingredients in VitaFLUX don’t pose much of a risk for most people. HerSolution pills, on the other hand, have one ingredient that we’re not thrilled by the inclusion of — dehydroepiandrosterone (DHEA). Even though HerSolution’s 25mg dose of DHEA technically puts it in the “possibly safe” category, it still has the potential to interact with a multitude of mental health prescriptions, and it may worsen psychiatric disorders (among other adverse effects).5 6 This doesn’t mean that HerSolution is unsafe when used as directed, but it does make it a riskier choice than alternatives without DHEA, like VitaFLUX. And all pill options mentioned in this guide, including Cake’s Libido Lift Rx and Drive For Her, may not be ideal for those on blood pressure medications, as nitric oxide has vasodilating effects.63 Cream and Jolt Gel pose fairly low risks for adverse effects. As with VitaFLUX, Jolt Gel has the potential to cause a herpes flare-up due to its L-arginine content (which is the case with HerSolution Gel, too).3 And OMG!

Before taking this medicine

If you’re a woman struggling with low libido or other sexual dysfunction concerns, you’re not alone. Research estimates that 10% of adult women live with Hypoactive Sexual Desire Disorder (HSDD), and other studies report that approximately 40-50% experience at least one distressing sexual symptom in their lives due to the hormone changes of menopause.1 2 These symptoms vary widely from person to person and can manifest both physically and mentally. Since these symptoms can be highly distressing and result in lowered self-esteem or relationship difficulties, you may be looking for the quickest fix possible. But with so many options on the market — a lot of which are from shady companies making impossible promises — how do you know which ones are effective and, most importantly, safe? In this guide to the best female arousal pills and topicals, we give you all the details of our top picks, including safety, effectiveness, cost, discounts, and much more. Cream may cause some minor side effects, like skin itching or irritation. Insider Tip: Based on our research, individuals who are pregnant or breastfeeding would be safest using a non-prescription OTC arousal gel, like Jolt Gel or HerSolution Gel. The ingredients in the supplements and the drugs in our prescription picks may harm your baby. For example, the pentoxifylline in Wisp’s OMG! Cream is an FDA Pregnancy Category C ingredient. (This means animal studies found the drug to have an “adverse effect on the fetus.”) Judging the effectiveness of products intended to support female libido poses a bit of a challenge — everyone reacts differently to different treatments.

What to avoid

“The lack of sexual interest isn’t something that ‘just happens’ with age or in relationships that a woman has to simply accept. It’s a treatable condition that should be addressed if a woman is inclined to do so.” A lot of factors can contribute to the loss of sexual interest. In a long-term relationship, excitement and passion tend to fade over time. Depression, anxiety, stress, sexual guilt or relationship problems can interfere with sexual interest. And physical factors such as hormonal imbalances or changes, neurotransmitter problems, and health issues such as an illness, injury or disability can all negatively affect sex drive.

Does it work?

For some women, a loss of sexual interest is acceptable: they’re comfortable in their relationship or their stage of life without it. In this case, there’s no need for treatment. However, if a loss of sexual interest causes personal distress, a woman should feel empowered to seek help. Medical treatments, including pharmaceuticals and cognitive behavior therapy, can help reignite the spark. Maintaining romance in a relationship can help inspire and support sexual attraction, connection and communication.

MACA EXTRACT

Small gestures of affection can help keep the connection, whether it’s hugging and holding hands, planning date nights or dressing to please your partner. In addition, staying as healthy as possible – through diet, exercise, personal care, positivity and socialization – help supports optimal sexual desire. Addyi and Vyleesi are nonhormonal medications for premenopausal women that work on neurotransmitters to improve sex drive. They are effective in about 60 percent of women. Addyi is a non-hormonal pill taken every night. For example, someone may experience fantastic results from HerSolution, while others may say it did absolutely nothing for them.

Natural performance boosters

Cognitive behavior therapy (CBT) can be used alone or in combination with pharmaceuticals to boost sexual interest. Cognitive behavior therapy works to change negative beliefs or thoughts about sexuality that can interfere with desire. When sex is good, it adds value; but when it’s bad or non-existent and causes distress, it can be extremely powerful in draining a relationship. If you experience distress, get help from a qualified medical provider with the expertise you need. Some, but not all OB/GYNs are well-educated in sexual desire treatment options.

What you can do

For postmenopausal care, look for a physician with NAMS (North American Menopause Society) or NCMP (Certified Menopause Practitioner) certification. Remember, you have a right to a healthy sexual life. If your provider doesn’t ask, feel free to start the conversation – or find a provider who will discuss the variety of options with you. The Female Sexual Health Program at University Hospitals is dedicated to addressing all of the sexual health concerns women may have throughout their lifetime. Our primary goal is to provide a unique and open environment of care where women feel empowered, confident and comfortable discussing this important aspect of their health. And the same can be said for the topical options or even the prescriptions approved by the FDA for the sole purpose of treating hypoactive sexual desire disorder (HSDD).7 8 Wisp, however, does something for its OMG!