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It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet. How do I know if I have premature ejaculation? What treatment is available for premature ejaculation?
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Males under the age of 18 years or older than 65 years old should not take Priligy. Priligy should not be taken by women. Do not drink grapefruit juice at least 24 hours prior to taking Priligy as this can increase the levels of the medication in your body. Avoid drinking alcohol while taking Priligy as consuming alcohol while taking Priligy can intensify dizziness, sleepiness, and slow reactions. Priligy can cause sleepiness, dizziness, fainting, trouble concentration, and blurred vision. Can I take erectile dysfunction drugs with dapoxetine (Priligy)? What are the side effects of dapoxetine (Priligy)? How can I reduce the risk of side effects of dapoxetine (Priligy)? Premature ejaculation (PE) is actually quite common. Up to 30% of men suffer with PE problems at some time in their life.
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It is recommended to take 30 mg of Priligy by mouth with a full glass of water 1 to 3 hours prior to sexual activity. Your dose may be increased to 60 mg by your doctor if applicable. Priligy should not be taken more than once a day. Dapoxetine, a selective serotonin reuptake inhibitor, is the active ingredient in Priligy. Lactose monohydrate, hypromellose, titanium dioxide (E171), triacetin, Iron Oxide Black (E172), Iron Oxide Yellow (E172) are contained in the coating of each Priligy tablet. It is usually related to stress and psychological factors rather than a physical problem.
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Avoid driving or operating heavy machinery until you know how the medication affects you. Talk to your doctor before taking Priligy if you are lactose intolerant. If you develop side effects that are persistent or troublesome, immediately talk to your doctor. The most common side effects associated with taking Priligy include the following: dizziness, headache, feeling sick, mood changes, numb or tingling sensation, difficulty getting or keeping an erection, excessive sweating or flushing, diarrhea, constipation, stomach pain, bloating, sleep problems, strange dreams, tiredness, sleepiness, nasal congestion, high blood pressure, difficulty concentration, shaking or trembling, low desire to have sex, ringing in the ears, blurred vision, indigestion, and dry mouth. IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. There are a variety of ways to help. Doctors define premature ejaculation as ejaculation in less than 2 minutes from penetration. However, if you ejaculate with very little stimulation, or before you want, and it is leading to relationship difficulties, you may benefit from treatment. There is medication available - dapoxetine (Priligy) - but there are also physical treatments such as extra thick condoms or anaesthetic (numbing) creams and sprays, and condoms pre-coated with numbing gel, which reduce penile sensitivity.
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body. The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug. Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. These can be bought in many pharmacies without the need for a prescription. As premature ejaculation is often linked to stress and psychological factors, psychological therapies can help. See NHS - Ejaculation problems or the book Coping with Premature Ejaculation: How to Overcome PE, Please Your Partner, and Have Great Sex (2004) by Michael E. Metz. There are a few medical conditions where it would be unsafe to take Priligy. Checks are carried out within the Priligy online consultation. The license for dapoxetine states that Viagra (sildenafil), Cialis (tadalafil), and other erectile dysfunction drugs should not be used together with Priligy as there is a risk of very low blood pressure. If you suffer from both erectile dysfunction (ED) and premature ejaculation (PE) try treatment for ED first and if you still have PE problems discuss this with your regular doctor who may be able to prescribe these together following a more in depth review. Priligy (dapoxetine) was developed after it was realised that a side effect of taking SSRI antidepressants was to prolong erections.
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Are allergic to dapoxetine or any of the other ingredients in Priligy Have a history of mania or severe depression Are taking monoamine oxidase inhibitors (MAOIs), thioridazine for treatment of schizophrenia, antidepressants, lithium, linezolid, tryptophan, St John's wort, tramadol, or migraine medications. If you are unsure whether you are taking any of these medications, ask your doctor. Before beginning treatment with Priligy, tell your doctor: If you take any medications, including all prescription and nonprescription medications, vitamins, and herbal supplements. If you have any medical conditions, including any other sexual disorders, low blood pressure, mental health problems, epilepsy, bleeding or blood clotting disorders, or kidney problems. Also tell your doctor if you use recreational drugs or if you have or are at risk of glaucoma. It was specifically designed as a short acting medication rather than an antidepressant but acts in the same way to increase serotonin levels in the brain, which delays ejaculation. It is washed out of the system within around 20 hours (half-life approximately 1.5 hours) and has no antidepressant effect. There are two strengths of dapoxetine (Priligy) tablets: 30mg and 60mg. You should start with the lower 30mg strength, taking the tablet 1-3 hours before sexual intercourse. Swallow the tablet whole, with a full glass of water. The strength of tablet can be increased the next time, if the lower dose does not have the desired response and you had no significant side effects. You should not take a dose more than once every 24 hours and do not take it every day. It is possible that grapefruit juice will cause the dapoxetine (Priligy) to stay in your system longer, so you should wait 24 hours after drinking grapefruit juice before taking dapoxetine. Grapefruit juice is a weak inhibitor of CYP3A4 gut wall metabolism, which can lead to a rise in levels of many drugs in your blood.
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When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount. Priligy (dapoxetine) is taken to manage premature ejaculation in adult men who are 18 to 64 years old. The information that comes with your Priligy prescription should be carefully read and followed. If you have any questions or concerns, talk with your doctor or pharmacist. Priligy is available in 30 mg and 60 mg oral tablets. Men usually get on well with dapoxetine (Priligy). The most common side effects are dizziness due to lower blood pressure, nausea, and headache. The full list of side effects is in the patient information leaflet. You are more likely to have side effects if taking alcohol, recreational drugs (such as LSD, heroin, methadone), or sleeping tablets at the same time as Priligy. There are some interactions with other drugs and some herbal remedies. The online consultation questionnaire checks if your medication is unsuitable to take with Priligy. Priligy is only licensed for use by men aged between 18 and 64 years. The effectiveness and safety of Priligy has not been established in patients aged 65 years and over. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption should not take dapoxetine (Priligy). Most men benefit from dapoxetine (Priligy), but psychological therapies and direct physical treatments can be used at the same time and may increase the benefit. Priligy was first launched in the UK in 2013 and remained under patent until October 2025, so only the drug company Menarini could produce and sell the medicine. When the patent expired, lower cost generic/unbranded versions became available and Menarini decided to no longer market Priligy. Dapoxetine is available on prescription in some NHS health authority areas, usually after specialist referral and advice - please check with your local GP surgery. NHS doctors will also usually be able to write private prescriptions for dapoxetine (charges will apply). Authored 28 July 2020 by Dr A. Reviewed by Dr C. Pugh, Dr B. Babor Last reviewed 19 June 2023 Last updated 3 December 2025 Editorial policy Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 14 Apr 2025 Dapoxetine is prescribed for the treatment of premature ejaculation. Take one tablet 1-3 hours before you have sex. The most common side-effects include feeling dizzy or faint, and feeling sick (nausea). Drinking a full glass of water at the same time as taking the tablet can reduce these effects. Premature ejaculation is the term used when a man orgasms (ejaculates) more quickly than he and/or his partner would like. For some men it can be temporary and can get better on its own; for others, prescribed treatments such as dapoxetine tablets can be helpful. Dapoxetine is a selective serotonin reuptake inhibitor medicine which has been specially developed for the treatment of premature ejaculation. It increases the time it takes to ejaculate and can improve the control over the ejaculation.